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KMID : 1024519990080020165
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Journal of the Environmental Sciences
1999 Volume.8 No. 2 p.165 ~ p.169
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Isolation and Identification of Aseptic Meningitis Virus in Pusan, 1998
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Cho Kyung-Soon
Kim Man-Soo
Jung Gu-Young
Min Sang-Kee
Ku Pyung-Tae
Kim Byung-Jun
Yoon Jae-Deuk
Jee Young-Mee
Kim Ki-Soon
Kim Young-Hee
Jeong Yong-Kee
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Abstract
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The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6.25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing antibody test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.
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KEYWORD
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aseptic meningitis, enterovirus, cytopathic effect, echovirus, coxsackievirus, neutralizing antibody test
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